Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity‐dependent regulatory mechanisms
نویسندگان
چکیده
منابع مشابه
synaptic neuronal plasticity
context the current study aimed to review research articles concerning cortical representational plasticity following the manipulations of inputs. evidence acquisition this review article compromised previous studies in pubmed, google scholar and scientific information databases according to the keywords since 1988. results ca1 neurons depolarization paired with ca3 presynaptic input result in ...
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Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the elucidation of its constituting mechanisms is of crucial importance in many aspects of normal and pathological brain function. In particular, a prominent aspect that r...
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The coordinated activation of a number of neuronal activity-regulated kinases is required for the full expression of LTP. Modulating the efficacy of synaptic transmission, such as occurs in LTP and LTD, is thought to be a cellular mechanism for storing information in the brain. In particular, a variety of pharmacological and genetic studies have established important roles for CaMKII and ERK in...
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Background & Aims: Change in visual experience impairs circadian rhythms. In this study, The effects of visual deprivation during critical period of brain development and melatonin intake on synaptic plasticity of hippocampal CA1 neurons were evaluated. Methods: This experimental study was done on male rats kept in standard 12 hour light/dark condition (L...
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The effect of ketamine (1-100 µM), which has NMDA receptor antagonist properties, on synaptic transmission and long-term potentiation (LTP) in CAl area of rat hippocampus was examined in vitro. Field potentials were recorded in pyramidal cell layer following Schaffer collateral stimulation. Primed-burst stimulation (PEs) was used for induction of LTP. The amplitude of population spiks (PS) was ...
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ژورنال
عنوان ژورنال: The FEBS Journal
سال: 2021
ISSN: 1742-464X,1742-4658
DOI: 10.1111/febs.15878